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    Lipophilin B Rabbit pAb (bs-6546R)  
    訂購熱線:400-901-9800
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    訂購QQ:  400-901-9800
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    50ul/1180.00元
    100ul/1980.00元
    200ul/2800.00元
    大包裝/詢價
    產品編號 bs-6546R
    英文名稱 Lipophilin B Rabbit pAb
    中文名稱 親脂性蛋白B抗體
    別    名 LIPB; LIPHB; Lipophilin B(uteroglobin family member) prostatein like; LipophilinB; LPHB; Prostatein like lipophilin B; SCGB1D2; Secretoglobin family 1D member 2; SG1D2_HUMAN.  
    研究領域 腫瘤  信號轉導  生長因子和激素  腫瘤細胞生物標志物  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    克 隆 號
    交叉反應 (predicted: Human)
    產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 8 kDa
    檢測分子量
    細胞定位 分泌型蛋白 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Lipophilin B: 41-90/90 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產品介紹 The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2.

    Function:
    May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones.

    Subcellular Location:
    Secreted

    Tissue Specificity:
    ighest expression was found in skeletal muscle. Expressed as well in thymus, trachea, kidney, steroid responsive tissues (prostate, testis, uterus, breast and ovary) and salivary gland.

    Similarity:
    Belongs to the secretoglobin family. Lipophilin subfamily.

    SWISS:
    O95969

    Gene ID:
    10647

    Database links:

    Entrez Gene: 10647 Human

    SwissProt: O95969 Human



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