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    Mimitin Rabbit pAb (bs-6551R)  
    訂購熱線:400-901-9800
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    50ul/1180.00元
    100ul/1980.00元
    200ul/2800.00元
    大包裝/詢價
    產品編號 bs-6551R
    英文名稱 Mimitin Rabbit pAb
    中文名稱 MYC誘導線粒體蛋白抗體
    別    名 mitochondrial; B17.2 like; B17.2-like; B17.2L; MIMIT_HUMAN; Mimitin; Mimitin mitochondrial; MMTN; Myc induced mitochondrial protein; Myc-induced mitochondrial protein; NADH dehydrogenase(ubiquinone) 1 alpha subcomplex assembly factor 2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2; NDUFA12 like; NDUFA12 like protein; NDUFA12-like protein; NDUFA12L; NDUFAF2.  
    研究領域 腫瘤  信號轉導  腫瘤細胞生物標志物  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    克 隆 號
    交叉反應 (predicted: Human,Mouse,Rat)
    產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 20 kDa
    檢測分子量
    細胞定位 細胞漿 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Mimitin: 71-169/169 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產品介紹 NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene cause progressive encephalopathy resulting from mitochondrial complex I deficiency.

    Function:
    Acts as a molecular chaperone for mitochondrial complex I assembly.

    Subunit:
    Mitochondrion.

    Subcellular Location:
    Highly expressed in ESCC cells. Also expressed in heart, skeletal muscle, liver, and in fibroblasts.

    DISEASE:
    Defects in NDUFAF2 are a cause of mitochondrial complex I deficiency (MT-C1D) [MIM:252010]. A disorder of the mitochondrial respiratory chain that causes a wide range of clinical disorders, from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease.

    Similarity:
    Belongs to the complex I NDUFA12 subunit family.

    SWISS:
    Q8N183

    Gene ID:
    91942

    Database links:

    Entrez Gene: 91942 Human

    Entrez Gene: 75597 Mouse

    Entrez Gene: 361894 Rat

    Omim: 609653 Human

    SwissProt: Q8N183 Human

    SwissProt: Q59J78 Mouse

    Unigene: 591757 Human

    Unigene: 276040 Mouse

    Unigene: 103613 Rat



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