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    DNAH7 Rabbit pAb (bs-11023R)  
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    50ul/1180.00元
    100ul/1980.00元
    200ul/2800.00元
    大包裝/詢價
    產品編號 bs-11023R
    英文名稱 DNAH7 Rabbit pAb
    中文名稱 軸絲動力蛋白7抗體
    別    名 axonemal; Axonemal beta dynein heavy chain 7; Ciliary dynein heavy chain 7; DNAH7; DYH7_HUMAN; Dynein axonemal heavy chain 7; Dynein heavy chain 7; Dynein heavy chain-like protein 2; HDHC2; KIAA0944.  
    Specific References  (1)     |     bs-11023R has been referenced in 1 publications.
    [IF=9.685] Wu, Huan. et al. DNALI1 deficiency causes male infertility with severe asthenozoospermia in humans and mice by disrupting the assembly of the flagellar inner dynein arms and fibrous sheath. CELL DEATH DIS. 2023 Feb;14(2):1-13  IF ;  Mouse,Human.  
    研究領域 神經生物學  信號轉導  細胞粘附分子  細胞外基質  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    克 隆 號
    交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse)
    產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 461 kDa
    檢測分子量
    細胞定位 細胞漿 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human DNAH7: 2301-2400/4024 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產品介紹 DNAH7 is a component of the inner dynein arm of ciliary axonemes (Zhang et al., 2002 [PubMed 11877439]).[supplied by OMIM, Mar 2008]

    Function:
    Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.

    Subunit:
    The dynein complex consists of at least two heavy chains and a number of intermediate and light chains (By similarity).

    Subcellular Location:
    Cytoplasm; cytoskeleton; cilium axoneme.

    Tissue Specificity:
    Detected in brain, testis and trachea. Detected in bronchial cells (at protein level).

    Similarity:
    Belongs to the dynein heavy chain family.

    SWISS:
    Q8WXX0

    Gene ID:
    56171

    Database links:

    Entrez Gene: 56171 Human

    Omim: 610061 Human

    SwissProt: Q8WXX0 Human

    Unigene: 97403 Human



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