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    APBB2 Rabbit pAb (bs-11627R)  
    訂購熱線:400-901-9800
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    50ul/1180.00元
    100ul/1980.00元
    200ul/2800.00元
    大包裝/詢價
    產品編號 bs-11627R
    英文名稱 APBB2 Rabbit pAb
    中文名稱 鐵蛋白Fe65樣蛋白1抗體
    別    名 Amyloid beta(A4) precursor protein-binding, family B, member 2(Fe65 like); Amyloid beta A4 precursor protein binding family B member 2; Amyloid beta A4 precursor protein-binding family B member 2; APBB 2; APBB2; APBB2_HUMAN; Fe65 like 1; Fe65 like; Fe65 like protein; FE65L 1; FE65L; FE65L1; Protein Fe65-like 1; Rirl 1; Rirl1; TR2 L; TR2L; Zfra; Zinc finger like protein.  
    研究領域 細胞生物  神經生物學  信號轉導  Alzheimer's  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    克 隆 號
    交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse)
    產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 83 kDa
    檢測分子量
    細胞定位 細胞核 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human APBB2: 251-350/758 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產品介紹 The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

    Function:
    May modulate the internalization of beta-amyloid precursor protein.

    Subunit:
    Binds to the intracellular domain of the beta-amyloid precursor protein.

    Similarity:
    Contains 2 PID domains.
    Contains 1 WW domain.

    SWISS:
    Q92870

    Gene ID:
    323

    Database links:

    Entrez Gene: 323 Human

    Entrez Gene: 11787 Mouse

    Omim: 602710 Human

    SwissProt: Q92870 Human

    SwissProt: Q9DBR4 Mouse

    Unigene: 479602 Human

    Unigene: 482700 Mouse

    Unigene: 5159 Mouse



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