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    RAMP3 Rabbit pAb (bs-11972R)  
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    50ul/1180.00元
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    產品編號 bs-11972R
    英文名稱 RAMP3 Rabbit pAb
    中文名稱 受體活性修飾蛋白3抗體
    別    名 Calcitonin receptor like receptor activity modifying protein 3; CRLR activity modifying protein 3; CRLR activity-modifying protein 3; OTTHUMP00000159549; OTTHUMP00000214279; OTTHUMP00000214280; Receptor(calcitonin) activity modifying protein 3; Receptor(G protein-coupled) activity modifying protein 3; Receptor activity modifying protein 3; RAMP3_HUMAN.  
    Specific References  (1)     |     bs-11972R has been referenced in 1 publications.
    [IF=1.86] Qiao, Xi, et al. "Intermedin is upregulated and attenuates renal fibrosis by inhibition of oxidative stress in rats with unilateral ureteral obstruction."Nephrology (2015).  WB ;  Rat.  
    研究領域 細胞生物  信號轉導  生長因子和激素  G蛋白偶聯受體  G蛋白信號  細胞膜蛋白  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    克 隆 號
    交叉反應 Human,Mouse
    產品應用 WB=1:500-2000,ELISA=1:5000-10000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 14 kDa
    檢測分子量
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human RAMP3: 51-148/148 <Extracellular>
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產品介紹 Calcitonin receptor like receptor activity modifying protein 3; CRLR activity modifying protein 3; CRLR activity-modifying protein 3; OTTHUMP00000159549; OTTHUMP00000214279; OTTHUMP00000214280; Receptor (calcitonin) activity modifying protein 3; Receptor (G protein-coupled) activity modifying protein 3; Receptor activity modifying protein 3.

    Function:
    RAMP3 (receptor calcitonin activity modifying protein 3) transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. It acts as a receptor for adrenomedullin (AM) together with CALCRL. It is strongly expressed in lung, breast, immune system and fetal tissues and belongs to the RAMP family.

    Subunit:
    Heterodimer of CALCRL and RAMP3

    Subcellular Location:
    Cell Membrane; Single-pass type I membrane protein

    Tissue Specificity:
    Strongly expressed in lung, breast, immune system and fetal tissues.

    Similarity:
    Belongs to the RAMP family.

    SWISS:
    O60896

    Gene ID:
    10268

    Database links:

    Entrez Gene: 10268 Human

    Omim: 605155 Human

    SwissProt: O60896 Human



    產品圖片
    25 ug total protein per lane of various lysates (see on figure) probed with RAMP3 polyclonal antibody, unconjugated (bs-11972R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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