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    DPP3 Rabbit pAb (bs-13029R)  
    訂購熱線:400-901-9800
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    50ul/1180.00元
    100ul/1980.00元
    200ul/2800.00元
    大包裝/詢價
    產品編號 bs-13029R
    英文名稱 DPP3 Rabbit pAb
    中文名稱 二肽氨基肽酶3抗體
    別    名 Dipeptidyl aminopeptidase III; Dipeptidyl arylamidase III; Dipeptidyl peptidase 3; Dipeptidyl peptidase III; DPP III; dpp3; DPP3_HUMAN; EC 3.4.14.4.  
    研究領域 腫瘤  細胞生物  信號轉導  泛素  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    克 隆 號
    交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Dog,Horse)
    產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 83 kDa
    檢測分子量
    細胞定位 細胞漿 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human DPP3: 1-100/737 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產品介紹 Dipeptidyl peptidases (DPPs) mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. DPP3 (dipeptidyl-peptidase 3), also known as DPPIII, is a zinc-exopeptidase that belongs to the peptidase M49 family. DPP3 localizes to the cytoplasm and is involved in intracellular protein catabolism. More specifically, DPP3 is an important enzyme involved in the degradation of enkephalins. An increase in the activity of DPP3 is implicated in ovarian and endometrial cancers.

    Function:
    Cleaves Arg-Arg-beta-naphthylamide.

    Subcellular Location:
    Cytoplasm.

    Similarity:
    Belongs to the peptidase M49 family.

    SWISS:
    Q9NY33

    Gene ID:
    10072

    Database links:

    Entrez Gene: 10072 Human

    Entrez Gene: 75221 Mouse

    Entrez Gene: 114591 Rat

    Omim: 606818 Human

    SwissProt: Q9NY33 Human

    SwissProt: Q99KK7 Mouse

    SwissProt: O55096 Rat



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