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    CD28 Rabbit pAb (bs-8865R)  
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
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    50ul/1180.00元
    100ul/1980.00元
    200ul/2800.00元
    大包裝/詢價
    產品編號 bs-8865R
    英文名稱 CD28 Rabbit pAb
    中文名稱 CD28抗體
    別    名 CD 28; CD28 antigen; CD28 molecule; MGC138290; T cell antigen CD28; T cell specific surface glycoprotein; T cell specific surface glycoprotein CD28; Tp44; CD28_HUMAN.  
    Specific References  (3)     |     bs-8865R has been referenced in 3 publications.
    [IF=3.549] Jingjing Li. et al. Circular RNA hsa_circ_0068252 functions in cisplatin resistance and immune response via miR-1304-5p/PD-L1 axis in non-small cell lung cancer. CHEMOTHERAPY. ;:  IA ;  Human.  
    [IF=3.098] Junli Zhang. et al. KCNQ1OT1 contributes to sorafenib resistance and programmed death?ligand?1?mediated immune escape via sponging miR?506 in hepatocellular carcinoma cells. Int J Mol Med. 2020 Nov;46(5):1794-1804  ELISA ;  Human.  
    [IF=3.057] Song et al. Forsythoside A Inhibits BVDV Replication via TRAF2-Dependent CD28-4-1BB Signaling in Bovine PBMCs. (2016) PLoS.On. 11:e0162791  WB ;  Cow.  
    研究領域 細胞生物  干細胞  細胞膜受體  細胞粘附分子  細胞表面分子  淋巴細胞  t-淋巴細胞  b-淋巴細胞  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    克 隆 號
    交叉反應 Mouse (predicted: Human,Rat)
    產品應用 WB=1:500-2000,ELISA=1:5000-10000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 25 kDa
    檢測分子量
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human CD28: 19-120/220 <Extracellular>
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產品介紹 The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]

    Function:
    Possibly involved in T-cell activation.

    Subunit:
    Homodimer; disulfide-linked. Interacts with DUSP14. Binds to CD80/B7-1 and CD86/B7-2/B70.

    Subcellular Location:
    Membrane; Single-pass type I membrane protein.

    Tissue Specificity:
    Expressed in T-cells and plasma cells, but not in less mature B-cells.

    Similarity:
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.

    SWISS:
    P10747

    Gene ID:
    940

    Database links:

    Entrez Gene: 940 Human

    Entrez Gene: 12487 Mouse

    Omim: 186760 Human

    SwissProt: P10747 Human

    SwissProt: P31041 Mouse

    SwissProt: P42069 Rabbit

    Unigene: 591629 Human

    Unigene: 255003 Mouse



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