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    ZBED4 Rabbit pAb (bs-13554R)  
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    產品編號 bs-13554R
    英文名稱 ZBED4 Rabbit pAb
    中文名稱 鋅指蛋白BED4抗體
    別    名 Zinc finger BED domain containing 4; Zinc finger BED domain containing protein 4; Zinc finger BED type containing 4; ZBED4_HUMAN.  
    研究領域 細胞生物  信號轉導  鋅指蛋白  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    克 隆 號
    交叉反應 Human (predicted: Mouse,Rat,Pig,Horse)
    產品應用 WB=1:500-2000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 130 kDa
    檢測分子量
    細胞定位 細胞核 細胞漿 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human ZBED4: 101-200/1171 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產品介紹 The zinc finger BED domain-containing protein family (ZBED) is comprised of ZBED1, ZBED2, ZBED3, ZBED4 and ZBED5. They each contain one BED-type zinc finger domains with the exception of ZBED4, which contain 4 BED-type zinc finger domains. ZBED1 is thought to function as a transcription factor that regulates a number of ribosomal protein (RP) encoded genes by binding specifically to 5'-TGTCG[CT]GA[CT]A-3' DNA regions found in RP promotors. ZBED3 is an Axin-binding protein involved in Wnt/beta-catenin signaling modulation. ZBED4 expression has been shown in human and mouse retinas where it is thought to act as a regulatory protein in cone photoreceptors and Müller cells. The functions of ZBED2 and ZBED5 have yet to be elucidated.

    Subunit:
    Homodimer.

    Subcellular Location:
    Cytoplasmic and Nuclear

    Tissue Specificity:
    Widely expressed with highest levels in testis, kidney and spinal cord and brain corpus callosum. Expressed in the retina, found in the cone photoreceptors, Mueller cells, cone pedicles and in the innermost retinal layer.

    Similarity:
    Contains 4 BED-type zinc fingers.

    SWISS:
    O75132

    Gene ID:
    9889

    Database links:

    Entrez Gene: 9889 Human

    Omim: 612552 Human

    SwissProt: O75132 Human

    Unigene: 475208 Human



    產品圖片
    Sample: U251 (human)cell Lysate at 40 ug Primary: Anti- ZBED4 (bs-13554R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 130 kD Observed band size: 135 kD
    Sample: U2os (human)cell Lysate at 40 ug Primary: Anti- ZBED4 (bs-13554R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 130 kD Observed band size: 130 kD
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