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    PTGFR Rabbit pAb (bs-10433R)  
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    產品編號 bs-10433R
    英文名稱 PTGFR Rabbit pAb
    中文名稱 前列腺素F2a受體抗體PGF2αR
    別    名 Prostaglandin F2 alpha Receptor PF2R_HUMAN; PGF receptor; PGF2 alpha receptor; PGF2-alpha receptor; Prostaglandin F receptor; Prostaglandin F2-alpha receptor; Prostaglandin receptor 2 alpha; Prostanoid FP receptor; PTGFR; FP; MGC120498; MGC46203.  
    Specific References  (1)     |     bs-10433R has been referenced in 1 publications.
    [IF=1.66] Xueqiang Qinet al. Effects of non-esterified fatty acids on relative abundance of prostaglandin E2 and F2α synthesis-related mRNA transcripts and protein in endometrial cells of cattle in vitro. Anim Reprod Sci . 2020 Oct;221:106549.  IF ;  Bovine.  
    研究領域 神經生物學  細胞膜受體  G蛋白偶聯受體  G蛋白信號  細胞膜蛋白  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    克 隆 號
    交叉反應 Human,Mouse (predicted: Rat,Rabbit,Dog,Horse)
    產品應用 WB=1:500-2000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 40 kDa
    檢測分子量
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human PTGFR: 121-220/359 <Extracellular>
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產品介紹 The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

    Function:
    Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum.

    Subcellular Location:
    Cell membrane; Multi-pass membrane protein.

    Similarity:
    Belongs to the G-protein coupled receptor 1 family.

    SWISS:
    P43088

    Gene ID:
    5737

    Database links:

    Entrez Gene: 5737 Human

    Omim: 600563 Human

    SwissProt: P43088 Human

    Unigene: 654365 Human



    產品圖片
    Protein: U2os(human) lysates at 40ug; Primary: Anti-PTGFR (bs-10433R) at 1:300; Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bse-0295G-HRP) at 1: 5000; ECL excitated the fluorescence; Predicted band size :40 kD Observed band size :50 kD
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