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    NOSIP Rabbit pAb (bs-16652R)  
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    50ul/1180.00元
    100ul/1980.00元
    200ul/2800.00元
    大包裝/詢價
    產品編號 bs-16652R
    英文名稱 NOSIP Rabbit pAb
    中文名稱 一氧化氮合成酶相互作用蛋白抗體
    別    名 CGI 25; CGI-25; NOSIP_HUMAN; CGI25; CGI25 protein; eNOS interacting protein; Nitric oxide synthase interacting protein.  
    研究領域 神經生物學  信號轉導  轉運蛋白  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    克 隆 號
    交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse)
    產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 33 kDa
    檢測分子量
    細胞定位 細胞核 細胞漿 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human NOSIP: 151-250/301 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產品介紹 The protein encoded by this gene may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2012]

    Function:
    NOSIP is a novel type of modulator that promotes translocation of eNOS from the plasma membrane to intracellular sites, thereby uncoupling eNOS from plasma membrane caveolae and inhibiting NO synthesis.

    Subunit:
    Interacts with NOS1 and NOS3.

    Subcellular Location:
    Cytoplasm. Nucleus. Note: Translocates from nucleus to cytoplasm in the G2 phase of the cell cycle.

    Tissue Specificity:
    Expressed in heart, brain and lung. Present in endothelial cells (at protein level).

    Similarity:
    Belongs to the NOSIP family.

    SWISS:
    Q9Y314

    Gene ID:
    51070

    Database links:

    Entrez Gene: 51070 Human

    Entrez Gene: 511234 Cow

    Entrez Gene: 66394 Mouse

    Entrez Gene: 292894 Rat

    SwissProt: Q3SWY5 Cow

    SwissProt: Q9Y314 Human

    SwissProt: Q9D6T0 Mouse



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