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    TMEM175 Rabbit pAb (bs-18922R)  
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    產品編號 bs-18922R
    英文名稱 TMEM175 Rabbit pAb
    中文名稱 跨膜蛋白175抗體
    別    名 MGC4618; Hypothetical protein DKFZp547K246; hypothetical protein LOC84286; Hypothetical protein MGC4618; TM175_HUMAN; tmem175; Transmembrane protein 175.  
    Specific References  (1)     |     bs-18922R has been referenced in 1 publications.
    [IF=5.682] Palomba, Nicole Piera. et al. Common and Rare Variants in TMEM175 Gene Concur to the Pathogenesis of Parkinson’s Disease in Italian Patients. MOL NEUROBIOL. 2023 Jan;:1-24  IHC ;  Mouse.  
    研究領域 細胞生物  免疫學  跨膜蛋白  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    克 隆 號
    交叉反應 Mouse,Rat (predicted: Human)
    產品應用 WB=1:500-2000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 56 kDa
    檢測分子量
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human TM175: 231-330/504 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產品介紹 TMEM175 (Transmembrane Protein 175) is a Protein Coding gene.

    Function:
    Organelle-specific potassium channel specifically responsible for potassium conductance in endosomes and lysosomes. Forms a potassium-permeable leak-like channel, which regulates lumenal pH stability and is required for autophagosome-lysosome fusion. Constitutes the major lysosomal potassium channel.

    Subunit:
    Homodimer.

    Subcellular Location:
    Membrane.

    Tissue Specificity:
    Widely expressed.

    Similarity:
    Belongs to the TMEM175 family.

    SWISS:
    Q9BSA9

    Gene ID:
    84286

    Database links:

    Entrez Gene: 84286 Human

    Entrez Gene: 72392 Mouse

    Entrez Gene: 305623 Rat

    SwissProt: Q9BSA9 Human

    SwissProt: Q9CXY1 Mouse

    SwissProt: Q6AY05 Rat

    Unigene: 478936 Human

    Unigene: 258324 Mouse

    Unigene: 159765 Rat



    產品圖片
    Sample: Lane 1: Cerebrum (Mouse) Lysate at 40 ug Lane 2: Kidney (Mouse) Lysate at 40 ug Lane 3: Liver (Mouse) Lysate at 40 ug Lane 4: Testis (Mouse) Lysate at 40 ug Lane 5: Lung (Mouse) Lysate at 40 ug Lane 6: Spleen (Mouse) Lysate at 40 ug Lane 7: Cerebral cortex (Rat) Lysate at 40 ug Lane 8: Liver (Rat) Lysate at 40 ug Lane 9: Testis (Rat) Lysate at 40 ug Primary: Anti-TMEM175 (bs-18922R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56/43 kD Observed band size: 45 kD
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