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    NAALADL1 Rabbit pAb (bs-18992R)  
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
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    50ul/1180.00元
    100ul/1980.00元
    200ul/2800.00元
    大包裝/詢價
    產品編號 bs-18992R
    英文名稱 NAALADL1 Rabbit pAb
    中文名稱 回腸絨毛刷狀緣膜蛋白抗體
    別    名 100 kDa ileum brush border membrane protein; I100; Ileal dipeptidylpeptidase; Ileal peptidase I100; N acetylated alpha linked acidic dipeptidase like 1; N-acetylated-alpha-linked acidic dipeptidase-like protein; NAALADase L; NAALADASEL; NAALADL.  
    研究領域 細胞生物  信號轉導  泛素  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    克 隆 號
    交叉反應 (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Dog,Horse)
    產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 81 kDa
    檢測分子量
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human NAALADL1: 501-600/740 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產品介紹 NAALADL1 is a 740 amino acid single-pass type II membrane protein that localizes to the apical cell membrane. Belonging to the peptidase M28 family and the M28B subfamily, NAALADL1 is mainly expressed in the distal small intestine but is also expressed in spleen and tesits. NAALADL1 is considered a novel ileal brush border membrane protein,NAALADL1 is thought to have dipeptidyl-peptidase IV type activity. NAALADL1 exists as eight alternatively spliced isoforms and is encoded by a gene located on human chromosome 11q13.1.

    Function:
    NAALADase-like activity unknown. Has no NAAG hydrolyzing activity. Exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.

    Subcellular Location:
    Apical cell membrane; Single-pass type II membrane protein. Note: Ileal brush border membrane.

    Tissue Specificity:
    Mainly expressed in the distal small intestine. Also expressed in the spleen and testis. Weak expression in the brain, locating mainly to the brain stem, amygdala, thalamus and ventral striatum. Isoform 2 and 3 isoform 3 are found in the small intestine and colon.

    Similarity:
    Belongs to the peptidase M28 family. M28B subfamily.

    SWISS:
    Q9UQQ1

    Gene ID:
    10004

    Database links:

    Entrez Gene: 10004 Human

    Omim: 602640 Human

    SwissProt: Q9UQQ1 Human



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