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    PLD3 Rabbit pAb (bs-12717R)  
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    產品編號 bs-12717R
    英文名稱 PLD3 Rabbit pAb
    中文名稱 膽堿磷酸酯酶3抗體
    別    名 Choline phosphatase 3; HindIII K4L homolog; HU K4; Hu-K4; HUK4; Phosphatidylcholine hydrolyzing phospholipase D3; Phosphatidylcholine-hydrolyzing phospholipase D3; phospholipase D family, member 3; phospholipase D3; PLD 3; PLD3; PLD3_HUMAN.  
    研究領域 腫瘤  細胞生物  神經生物學  信號轉導  Alzheimer's  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    克 隆 號
    交叉反應 Mouse (predicted: Human,Rat,Rabbit,Sheep,Cow)
    產品應用 WB=1:500-2000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 55 kDa
    檢測分子量
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human PLD3: 201-300/490 
    亞    型
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產品介紹 This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2014]

    Subcellular Location:
    Endoplasmic reticulum membrane.

    Tissue Specificity:
    Widely expressed. Expressed at higher level in brain. Expressed at low level in corpus callosum, suggesting that it is highly expressed in neurons.

    Post-translational modifications:
    Glycosylated.

    Similarity:
    Belongs to the phospholipase D family.
    Contains 2 PLD phosphodiesterase domains.

    SWISS:
    Q8IV08

    Gene ID:
    23646

    Database links:

    Entrez Gene: 23646 Human

    Entrez Gene: 18807 Mouse

    Entrez Gene: 361527 Rat

    SwissProt: Q2KJJ8 Cow

    SwissProt: Q8IV08 Human

    SwissProt: O35405 Mouse

    SwissProt: Q5FVH2 Rat

    Unigene: 257008 Human

    Unigene: 6483 Mouse

    Unigene: 128036 Rat



    產品圖片
    Sample: Cerebrum (Mouse) Lysate at 40 ug Primary: Anti-LD3? (bs-12717R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kD Observed band size: 55 kD
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