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    mouse CD117(c-Kit)/Pacific Blue (bsm-30165A-Pacific Blue)  
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    產品編號 bsm-30165A-Pacific Blue
    英文名稱 mouse CD117(c-Kit)/Pacific Blue
    中文名稱 Pacific Blue標記小鼠CD117單克隆抗體
    別    名 C Kit; CD 117; CD117; CD117 antigen; KIT; KIT_HUMAN; Mast/stem cell growth factor receptor; Mast/stem cell growth factor receptor Kit; p145 c-kit; PBT; Piebald trait protein; Proto oncogene c Kit; Proto oncogene tyrosine protein kinase Kit; Proto-oncogene c-Kit; SCF Receptor; SCFR; soluble KIT variant 1; Stem cell factor receptor; tyrosine protein kinase Kit; Tyrosine-protein kinase Kit; v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog; v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog.  
    抗體來源 Rat
    克隆類型 Monoclonal
    克 隆 號 4B5
    交叉反應
    產品應用
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 105kDa
    檢測分子量 145
    性    狀 Liquid
    亞    型 Rat IgG2b, k
    純化方法 Affinity purified by Protein G
    緩 沖 液 0.01M PBS, 0.5%BSA, 0.03% Proclin300
    保存條件 Store at 2-8℃. Protect from light. Avoid freezing.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產品介紹 This gene encodes a receptor tyrosine kinase. This gene was initially identified as a homolog of the feline sarcoma viral oncogene v-kit and is often referred to as proto-oncogene c-Kit. The canonical form of this glycosylated transmembrane protein has an N-terminal extracellular region with five immunoglobulin-like domains, a transmembrane region, and an intracellular tyrosine kinase domain at the C-terminus. Upon activation by its cytokine ligand, stem cell factor (SCF), this protein phosphorylates multiple intracellular proteins that play a role in in the proliferation, differentiation, migration and apoptosis of many cell types and thereby plays an important role in hematopoiesis, stem cell maintenance, gametogenesis, melanogenesis, and in mast cell development, migration and function. This protein can be a membrane-bound or soluble protein. Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2020]

    SWISS:
    P05532

    Gene ID:
    16590

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