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    NSE Mouse mAb (V1802)  
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    定制/大包裝/詢價
    大包裝/詢價
    產品編號 V1802
    英文名稱 NSE Mouse mAb
    中文名稱 神經元特異性烯醇化酶單克隆抗體
    別    名 Gamma-enolase; Gamma enolase; Neural enolase; Neuron specific enolase; neurone-specific enolase; 2 phospho D glycerate hydrolyase; Eno 2; Eno2; ENO2; ENOG; Enolase 2; Enolase 2 gamma neuronal; Enolase2; Neuron specific enolase; Neuron specific gamma enolase; NSE; ENOG_HUMAN; Gamma-enolase; 2-phospho-D-glycerate hydro-lyase; enolase 2, gamma, neuronal.  γ 烯醇化酶
    克 隆 號
    理論分子量 48 kDa
    檢測分子量
    細胞定位 細胞漿 細胞膜 
    性    狀 Liquid
    濃    度 ≥1mg/ml
    緩 沖 液 0.01M PBS (pH7.4).
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    產品介紹 Gamma-enolase, also known as enolase 2 (ENO2) or neuron specific enolase (NSE), is an enzyme that in humans is encoded by the ENO2 gene. Gamma-enolase is a phosphopyruvate hydratase. Gamma-enolase is one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates.

    Function:
    Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.

    Subunit:
    Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific.

    Subcellular Location:
    Cytoplasm. Cell membrane. Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form.

    Tissue Specificity:
    The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.

    Similarity:
    Belongs to the enolase family.

    SWISS:
    P09104

    Gene ID:
    2026

    Database links:

    Entrez Gene: 2026 Human

    Entrez Gene: 13807 Mouse

    Entrez Gene: 24334 Rat

    Omim: 131360 Human

    SwissProt: P09104 Human

    SwissProt: P17183 Mouse

    SwissProt: P07323 Rat

    Unigene: 511915 Human



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