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    Rabbit Anti-THOP1/PE Conjugated antibody (bs-11683R-PE)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul  
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-11683R-PE
    英文名稱 Rabbit Anti-THOP1/PE Conjugated antibody
    中文名稱 PE標記的Thimet內肽酶抗體
    別    名 Thimet Oligopeptidase; Endopeptidase 24.15; EP24.15; MEPD_HUMAN; MP78; Thimet oligopeptidase 1; Thop1; THOP1_HUMAN; EC 3.4.24.15.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul  
    研究領域 細胞生物  神經生物學  Alzheimer's  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 (predicted: Human, Mouse, Rat, Dog, Horse, )
    產品應用 ICC=1:50-200 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 79kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Thimet Oligopeptidase
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產品介紹 background:
    Thimet oligopeptidase, also designated soluble metallo-endopeptidase, is a cytoplasmic protein belonging to the peptidase M3 family. The gene for the protein maps against chromosome 19q13.3. Thimet oligopeptidase can degrade the b-Amyloid precursor protein and generate amyloidogenic fragments. It is important in cytoplasmic peptide degradation and involved in metabolism of neuropeptides that are less than 20 amino acids in length. Thimet oligopeptidase is highly expressed in testis but can also be detected in liver, lung and kidney.

    Function:
    Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.

    Subunit:
    Monomer.

    Subcellular Location:
    Cytoplasm.

    Similarity:
    Belongs to the peptidase M3 family.

    Database links:

    Entrez Gene: 7064 Human

    Entrez Gene: 50492 Mouse

    Entrez Gene: 64517 Rat

    Omim: 601117 Human

    SwissProt: P52888 Human

    SwissProt: Q8C1A5 Mouse

    SwissProt: P24155 Rat

    Unigene: 78769 Human

    Unigene: 26995 Mouse

    Unigene: 9490 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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