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    Rabbit Anti-NARC1/PCSK9/Cy7 Conjugated antibody (bs-6060R-Cy7)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul  
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-6060R-Cy7
    英文名稱 Rabbit Anti-NARC1/PCSK9/Cy7 Conjugated antibody
    中文名稱 Cy7標記的神經細胞凋亡調節轉化蛋白1/前蛋白轉化酶枯草溶菌素9抗體
    別    名 FH3; HCHOLA3; Hypercholesterolemia autosomal dominant 3; NARC 1; NARC-1; NARC1; Neural apoptosis regulated convertase 1; Neural apoptosis-regulated convertase 1; PC 9; PC9; PCSK 9; PCSK9; PCSK9_HUMAN; Proprotein convertase 9; Proprotein convertase PC9; Proprotein convertase subtilisin/kexin type 9; PSEC0052; Subtilisin/kexin like protease PC9; Subtilisin/kexin-like protease PC9.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul  
    研究領域 心血管  細胞生物  免疫學  神經生物學  信號轉導  干細胞  細胞凋亡  轉錄調節因子  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 Mouse, Rat,  (predicted: Human, )
    產品應用
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 57kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human PCSK9/NARC1
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產品介紹 background:
    May be implicated in the differentiation of cortical neurons and may play a role in cholesterol homeostasis.

    Function:
    The precursor protein but not the mature protein may form multimers.

    Subunit:
    The precursor protein but not the mature protein may form multimers.

    Subcellular Location:
    Secreted.

    Tissue Specificity:
    Expressed in neuro-epithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells.

    Post-translational modifications:
    The soluble zymogen undergoes autocatalytic intramolecular processing in the endoplasmic reticulum, resulting in the cleavage of its propeptide that remains associated with the secreted enzyme.

    Similarity:
    Belongs to the peptidase S8 family.
    Contains 1 peptidase S8 domain.

    Database links:

    Entrez Gene: 255738 Human

    Entrez Gene: 100102 Mouse

    Entrez Gene: 298296 Rat

    Omim: 607786 Human

    SwissProt: Q8NBP7 Human

    SwissProt: Q80W65 Mouse

    SwissProt: P59996 Rat

    Unigene: 18844 Human

    Unigene: 133268 Mouse

    Unigene: 19195 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    前蛋白轉化酶枯草溶菌素9(PCSK9)是近年來新發現的一種與調節脂質代謝密切相關的基因,編碼前蛋白轉化酶NARC-1。Narc-1/pcsk9可通過調節細胞表面的低密度脂蛋白受體(LDLR)水平,參與脂質代謝,從而在動脈粥樣硬化性疾病的發生、發展中發揮重要作用。
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