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    Rabbit Anti-TKTL1/Gold Conjugated antibody (bs-6284R-Gold)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul(10nm  15nm  35nm
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-6284R-Gold
    英文名稱 Rabbit Anti-TKTL1/Gold Conjugated antibody
    中文名稱 膠體金標記的酮基移換酶樣蛋白1抗體
    別    名 TK 2; TK2; TKR; TKT 2; TKT2; TKTL1; TKTL1_HUMAN; Transketolase 2; Transketolase like 1; Transketolase like protein 1; Transketolase related protein; Transketolase-like protein 1; Transketolase-related protein; Transketolase2.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul(10nm  15nm  35nm
    研究領域 腫瘤  信號轉導  腫瘤細胞生物標志物  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
    產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 65 kDa
    性    狀 Lyophilized or Liquid
    濃    度 0.4mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human TKTL1
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
    保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
    產品介紹 background:
    The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene.

    Function:
    Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate

    Subunit:
    Homodimer

    Subcellular Location:
    Cytoplasm. Nucleus. Note=Predominantly cytoplasmic and to a lesser extent also nuclear.

    Tissue Specificity:
    Expressed in fetal and adult heart, brain, lung, liver, and kidney, and in adult placenta, skeletal muscle and pancreas. Up-regulated in various epithelial tumors.

    Similarity:
    Belongs to the transketolase family.

    Database links:

    Entrez Gene: 8277 Human

    Omim: 300044 Human

    SwissProt: P51854 Human

    Unigene: 102866 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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