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    Rabbit Anti-SKALP/Biotin Conjugated antibody (bs-6531R-Bio)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul  
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-6531R-Bio
    英文名稱 Rabbit Anti-SKALP/Biotin Conjugated antibody
    中文名稱 生物素標記的彈性蛋白酶抑制劑抗體
    別    名 ELAF_HUMAN; Elafin; Elastase Specific Inhibitor; Elastase-specific inhibitor; ES 1; ESI; Peptidase inhibitor 3; PI 3; PI-3; PI3; Protease inhibitor 3 skin derived; Protease inhibitor WAP3; SKALP; Skin derived Anti leukoproteinase; Skin-derived antileukoproteinase; Trappin 2; WAP four disulfide core domain protein 14; WAP four-disulfide core domain protein 14; WFDC14.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul  
    研究領域 腫瘤  細胞生物  免疫學  信號轉導  細菌及病毒  腫瘤細胞生物標志物  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 (predicted: Human, Mouse, Rat, Dog, Horse, )
    產品應用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 13kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human SKALP/Elafin
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產品介紹 background:
    This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines. [provided by RefSeq, Oct 2008]

    Function:
    Neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis.

    Subcellular Location:
    Secreted.

    Similarity:
    Contains 1 WAP domain.

    Database links:

    Entrez Gene: 5266 Human

    Omim: 182257 Human

    SwissProt: P19957 Human

    Unigene: 112341 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    Elafin,又稱SKALP(Skin-derived antileucoproteinase)或彈性蛋白酶特異性抑制劑(Elastase-Specific Inhibitor,ESI),它是一種低分子量的彈性蛋白酶抑制劑。它屬于“trappin”蛋白家族Trappin-2,具有拮抗胰彈性蛋白酶、中性粒細胞彈性蛋白酶(NE)和蛋白酶3的作用。
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