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    Rabbit Anti-MMP10/FITC Conjugated antibody (bs-1344R-FITC)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul  
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-1344R-FITC
    英文名稱 Rabbit Anti-MMP10/FITC Conjugated antibody
    中文名稱 FITC標記的基質金屬蛋白酶-10抗體
    別    名 Matrix metalloproteinase 10; Matrix metalloproteinase-10; matrix metalloproteinase 10; MMP-10; Mmp10; MMP10_HUMAN; SL 2; SL2; STMY 2; Stromelysin 2; Stromelysin II; Stromelysin-2; Stromelysin2; StromelysinII; Transin 2; Transin-2; Transin2; stromelysin 2; SL-2; STMY2; MMP 10; AV377895, MMP10.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul  
    研究領域 腫瘤  心血管  細胞生物  細胞外基質  泛素  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 Human,  (predicted: Mouse, Rat, )
    產品應用 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 43kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human MMP10
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產品介紹 background:
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

    Function:
    Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.

    Subcellular Location:
    Secreted, extracellular space, extracellular matrix (Probable).

    Similarity:
    Belongs to the peptidase M10A family.
    Contains 4 hemopexin-like domains.

    Database links:

    Entrez Gene: 4319 Human

    Entrez Gene: 17384 Mouse

    Entrez Gene: 117061 Rat

    Omim: 185260 Human

    SwissProt: P09238 Human

    SwissProt: O55123 Mouse

    SwissProt: P07152 Rat

    Unigene: 2258 Human

    Unigene: 14126 Mouse

    Unigene: 9946 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    合成與降解(Synthesis and Degradation)
    MMP10主要用于一些惡性腫瘤,如乳腺癌、胃腸道癌、卵巢癌等與轉移浸潤的研究。
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