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    產品中心-北京博奧森生物技術有限公司
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    Rabbit Anti-Calumenin/Gold Conjugated antibody (bs-6658R-Gold)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul(10nm  15nm  35nm
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-6658R-Gold
    英文名稱 Rabbit Anti-Calumenin/Gold Conjugated antibody
    中文名稱 膠體金標記的鈣腔蛋白
    別    名 CALU; CALU_HUMAN; Calumenin; Crocalbin; crocalbin-like protein; multiple EF-hand protein.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul(10nm  15nm  35nm
    研究領域 信號轉導  轉錄調節因子  結合蛋白  細胞類型標志物  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, Rabbit, )
    產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 35kDa
    性    狀 Lyophilized or Liquid
    濃    度 0.4mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Calumenin
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
    保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
    產品介紹 background:
    Involved in regulation of vitamin K-dependent carboxylation of multiple amino-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity.


    Function:
    Involved in regulation of vitamin K-dependent carboxylation of multiple amino-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity.

    Subunit:
    Interacts with GGCX.

    Subcellular Location:
    Endoplasmic reticulum lumen. Secreted. Melanosome. Sarcoplasmic reticulum lumen. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

    Tissue Specificity:
    Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver.

    Similarity:
    Belongs to the CREC family.
    Contains 6 EF-hand domains.

    Database links:

    Entrez Gene: 813 Human

    Entrez Gene: 12321 Mouse

    Entrez Gene: 64366 Rat

    Omim: 603420 Human

    SwissProt: O43852 Human

    SwissProt: O35887 Mouse

    SwissProt: O35783 Rat

    Unigene: 592258 Human

    Unigene: 7753 Human

    Unigene: 392075 Mouse

    Unigene: 1841 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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