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    Rabbit Anti-Transferrin/Cy3 Conjugated antibody (bs-2052R-Cy3)
    訂購熱線:400-901-9800
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    訂購QQ:  400-901-9800
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    說 明 書: 100ul  
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-2052R-Cy3
    英文名稱 Rabbit Anti-Transferrin/Cy3 Conjugated antibody
    中文名稱 Cy3標記的轉鐵蛋白/血清鐵傳遞蛋白抗體
    別    名 Apotransferrin; Beta 1 metal binding globulin; DKFZp781D0156; PRO1400; PRO1557; PRO2086; Serotransferrin precursor; Siderophilin; TF; Transferin; Transferrin; TRFE_HUMAN; Beta-1 metal-binding globulin; Serotransferrin.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul  
    研究領域 心血管  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 (predicted: Human, )
    產品應用
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 77kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 Full length native Transferrin protein purified from human plasma
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產品介紹 background:
    This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009].

    Function:
    Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.

    Subunit:
    Monomer.

    Subcellular Location:
    Secreted.

    Tissue Specificity:
    Expressed by the liver and secreted in plasma.

    DISEASE:
    Defects in TF are the cause of atransferrinemia (ATRAF) [MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia.

    Similarity:
    Belongs to the transferrin family.
    Contains 2 transferrin-like domains.

    Database links:

    Entrez Gene: 7018 Human

    Entrez Gene: 22041 Mouse

    Entrez Gene: 24825 Rat

    Omim: 190000 Human

    SwissProt: P02787 Human

    SwissProt: Q921I1 Mouse

    SwissProt: P12346 Rat

    Unigene: 518267 Human

    Unigene: 37214 Mouse

    Unigene: 91296 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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