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    Rabbit Anti-BAI1/Cy7 Conjugated antibody (bs-7513R-Cy7)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul  
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-7513R-Cy7
    英文名稱 Rabbit Anti-BAI1/Cy7 Conjugated antibody
    中文名稱 Cy7標記的腦特異性血管生成抑制蛋白1抗體
    別    名 BAI 1; BAI-1; Brain specific angiogenesis inhibitor 1; mKIAA4089; KIAA4089; R75078; B830018M07Rik; BAI1_HUMAN  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul  
    研究領域 心血管  細胞生物  免疫學  血管內皮細胞  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Sheep, )
    產品應用
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 170kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human BAI1
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產品介紹 background:
    BAI 1 protein is likely to be a potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of glioblastoma. It may function in cell adhesion and signal transduction in the brain. Reduced or no expression is observed in some glioblastoma cell lines and cancer tissues.

    Function:
    Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Likely to be a potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of glioblastoma. May function in cell adhesion and signal transduction in the brain.

    Subunit:
    Interacts with ELMO1 and DOCK1. When bound to ELMO1 and DOCK1, it may act as a module to promote the engulfment. Interacts with MAGI1, MAGI3, BAIAP2 and PHYHIP.

    Subcellular Location:
    Cell membrane; Multi-pass membrane protein. Note=Likely to be concentrated at cell-cell adhesion sites.

    Tissue Specificity:
    Specifically expressed in brain. Reduced or no expression is observed in some glioblastoma cell lines and cancer tissues. No expression in astrocytes.

    Post-translational modifications:
    The endogenous protein is proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit.

    Similarity:
    Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    Contains 1 GPS domain.
    Contains 5 TSP type-1 domains.

    Database links:

    Entrez Gene: 524070 Cow

    Entrez Gene: 575 Human

    Entrez Gene: 107831 Mouse

    Entrez Gene: 362931 Rat

    Omim: 602682 Human

    SwissProt: O14514 Human

    SwissProt: Q3UHD1 Mouse

    Unigene: 194654 Human

    Unigene: 43133 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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