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    Rabbit Anti-Zfp91/Gold Conjugated antibody (bs-1941R-Gold)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul(10nm  15nm  35nm
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-1941R-Gold
    英文名稱 Rabbit Anti-Zfp91/Gold Conjugated antibody
    中文名稱 膠體金標記的白血病相關新基因抗體
    別    名 zinc finger protein 91; FKSG11; HGNC:14983; PZF; zinc finger protein 91 homolog (mouse); zinc finger protein homologous to mouse Zfp91; ZFP91_HUMAN.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul(10nm  15nm  35nm
    研究領域 腫瘤  細胞生物  免疫學  染色質和核信號  神經生物學  細胞凋亡  轉錄調節因子  結合蛋白  細胞分化  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Sheep, )
    產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 63kDa
    性    狀 Lyophilized or Liquid
    濃    度 0.4mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Zfp91
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
    保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
    產品介紹 background:
    The protein encoded by ZFP91 is a member of the zinc finger family of proteins. This protein contains C2H2 type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. May be involved in transcriptional regulation. May play an important role in cell proliferation and/or anti-apoptosis Found in all the examined tissues including brain, heart, kidney, lung, liver, spleen, thymus, skeletal muscle, ovary and testis. Belongs to the krueppel C2H2-type zinc-finger protein family.

    Function:
    Atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis.

    Subunit:
    Interacts with MAP3K14/NIK.

    Subcellular Location:
    Nucleus.

    Tissue Specificity:
    Expressed ubiquitously, particularly at high level in testis. Isoform 2 is testis specific.

    Similarity:
    Belongs to the krueppel C2H2-type zinc-finger protein family.
    Contains 5 C2H2-type zinc fingers.

    Database links:

    Entrez Gene: 80829 Human

    Entrez Gene: 109910 Mouse

    Entrez Gene: 246282 Rat

    SwissProt: Q96JP5 Human

    SwissProt: Q62511 Mouse

    Unigene: 524920 Human

    Unigene: 290924 Mouse

    Unigene: 1772 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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