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    Rabbit Anti-Apelin Receptor/Cy7 Conjugated antibody (bs-2430R-Cy7)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul  
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-2430R-Cy7
    英文名稱 Rabbit Anti-Apelin Receptor/Cy7 Conjugated antibody
    中文名稱 Cy7標記的血管緊張素II受體樣蛋白1抗體
    別    名 APJ receptor; AGTR L1; AGTRL 1; AGTRL1; Angiotensin II receptor like 1; Angiotensin receptor like 1; Apelin receptor; APJ; B78; FLJ90771; G protein coupled receptor APJ; GPCR34; HG 11; HG11; MGC45246; MSR; msr/apj; Aplnr; Agtrl1; APLNR; FLJ96609; APJ_HUMAN.  
    Journal
    PMID
    IF
    Application
    [IF=3.434] Lu Dinggui. et al. Apelin Alleviates Meniscus Endothelial Cell Apoptosis in Osteoarthritis. Dis Markers. 2022;2022:3556372  FC ;  Human.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul  
    研究領域 心血管  細胞生物  免疫學  G蛋白偶聯受體  G蛋白信號  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 Mouse,  (predicted: Human, Rat, Dog, Rabbit, )
    產品應用
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 42kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Apelin receptor
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產品介紹 background:
    This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq

    Function:
    Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.

    Subcellular Location:
    Cell membrane.

    Tissue Specificity:
    Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon.

    Similarity:
    Belongs to the G-protein coupled receptor 1 family.

    Database links:

    Entrez Gene: 429337 Chicken

    Entrez Gene: 615435 Cow

    Entrez Gene: 187 Human

    Entrez Gene: 23796 Mouse

    Entrez Gene: 83518 Rat

    Omim: 600052 Human

    SwissProt: P35414 Human

    SwissProt: Q9WV08 Mouse

    SwissProt: Q9JHG3 Rat

    Unigene: 438311 Human

    Unigene: 29368 Mouse

    Unigene: 7965 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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