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    Rabbit Anti-Osteocalcin/Gold Conjugated antibody (bs-4917R-Gold)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul(10nm  15nm  35nm
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-4917R-Gold
    英文名稱 Rabbit Anti-Osteocalcin/Gold Conjugated antibody
    中文名稱 膠體金標記的骨鈣蛋白/骨鈣素抗體
    別    名 Osteocalcin Propeptide; Osteocalcin; Osteocalcin precursor; Gamma-carboxyglutamic acid-containing protein; Bone Gla-protein; BGLAP; Bone gamma carboxyglutamate protein; BGLAP; BGP; Bone gamma carboxyglutamate gla protein osteocalcin; Bone gamma carboxyglutamate protein; Bone Gla protein; Gamma carboxyglutamic acid containing protein; OC; PMF1; OSTCN_HUMAN.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul(10nm  15nm  35nm
    研究領域 細胞生物  信號轉導  干細胞  細胞外基質  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, )
    產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 11kDa
    性    狀 Lyophilized or Liquid
    濃    度 0.4mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Osteocalcin
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
    保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
    產品介紹 background:
    Osteocalcin belongs to the osteocalcin/matrix Gla protein family and constitutes 1 to 2% of the total bone protein. It is a 49 amino acid single chain vitamin K dependent protein, made by osteoblasts, and is a major component of the noncollagenous bone matrix. Post translational modification by a vitamin K dependent carboxylase produces three gamma carboxyglutamic acid residues at positions 17, 21 and 24, giving it a high affinity for calcium. It also binds strongly to apatite.

    Function:
    Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.

    Subcellular Location:
    Secreted.

    Post-translational modifications:
    Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.

    Similarity:
    Belongs to the osteocalcin/matrix Gla protein family.
    Contains 1 Gla (gamma-carboxy-glutamate) domain.

    Database links:

    Entrez Gene: 281646 Cow

    Entrez Gene: 632 Human

    Entrez Gene: 397530 Pig

    Entrez Gene: 25295 Rat

    Omim: 112260 Human

    SwissProt: P02820 Cow

    SwissProt: P02818 Human

    SwissProt: Q8HYY9 Pig

    SwissProt: P04640 Rat

    Unigene: 654541 Human

    Unigene: 9722 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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