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    Rabbit Anti-Junctophilin 4/PE Conjugated antibody (bs-11084R-PE)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul  
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-11084R-PE
    英文名稱 Rabbit Anti-Junctophilin 4/PE Conjugated antibody
    中文名稱 PE標記的連接蛋白JPH4抗體
    別    名 JP-4; Jph4; JPH4_HUMAN; JPHL1; Junctophilin4; Junctophilin like 1 protein; Junctophilin-4; Junctophilin-like 1 protein; KIAA1831.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul  
    研究領域 發育生物學  神經生物學  細胞膜蛋白  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, )
    產品應用 ICC=1:50-200 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 66kDa
    細胞定位 細胞膜 
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Junctophilin 4
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產品介紹 background:
    This gene encodes a member of the junctophilin family of transmembrane proteins that are involved in the formation of the junctional membrane complexes between the plasma membrane and the endoplasmic/sarcoplasmic reticulum in excitable cells. The encoded protein contains a conserved N-terminal repeat region called the membrane occupation and recognition nexus sequence that is found in other members of the junctophilin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]

    Function:
    Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH4 is brain-specific and appears to have an active role in certain neurons involved in motor coordination and memory (By similarity).

    Subcellular Location:
    Cell membrane; Peripheral membrane protein (By similarity). Endoplasmic reticulum membrane; Single-pass type IV membrane protein (By similarity). Note=Localized predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic reticulum membrane, while the N-terminal part associates with the plasma membrane (By similarity).

    Similarity:
    Belongs to the junctophilin family.
    Contains 8 MORN repeats.

    Database links:

    Entrez Gene: 84502 Human

    Entrez Gene: 319984 Mouse

    Entrez Gene: 445271 Rat

    SwissProt: Q96JJ6 Human

    SwissProt: Q80WT0 Mouse

    SwissProt: Q69FB3 Rat

    Unigene: 597841 Human

    Unigene: 19047 Mouse

    Unigene: 163297 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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