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    Rabbit Anti-Fascin-3/PE Conjugated antibody (bs-11285R-PE)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul  
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-11285R-PE
    英文名稱 Rabbit Anti-Fascin-3/PE Conjugated antibody
    中文名稱 PE標記的肌動蛋白結合蛋白Fascin3抗體
    別    名 Fascin (testis); Fascin 3; Fascin homolog 3 actin bundling protein testicular (Strongylocentrotus purpuratus) ; Fascin homolog 3 actin bundling protein testicular; Fascin3; FSCN 3; FSCN3; MGC94950; Testis fascin; FSCN3_HUMAN.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul  
    研究領域 信號轉導  細胞骨架  細胞外基質  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Sheep, )
    產品應用 ICC=1:50-200 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 57kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Fascin-3
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產品介紹 background:
    Cell adhesion to extracellular matrix is an important physiological stimulus for organization of the Actin-based cytoskeleton. Adhesion to the matrix glycoprotein Thrombospondin 1 triggers the sustained formation of F-Actin microspikes that contain the Actin-bundling protein Fascin. These structures are also implicated in cell migration, which may be an important function of Thrombospondin 1 in tissue remodelling and wound repair. Fascin bundles Actin microfilaments within dynamic cellular structures such as microspikes, stress fibers and membrane ruffles. Fascin could serve as a prognostic factor for abnormal ovarian epithelial pathology and could be a novel target for the treatment of ovarian cancer. Fascin, an Actin-bundling protein, identifies dendritic cells in the blood and in tissues.

    Function:
    Acts as an actin bundling protein (By similarity).

    Subcellular Location:
    Cytoplasm, cytoskeleton (By similarity).

    Tissue Specificity:
    Expressed in testis.

    Similarity:
    Belongs to the fascin family.

    Database links:

    Entrez Gene: 29999 Human

    Entrez Gene: 56223 Mouse

    SwissProt: Q9NQT6 Human

    SwissProt: Q9QXW4 Mouse

    Unigene: 712692 Human

    Unigene: 31708 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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