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    Rabbit Anti-NPRC/Cy5.5 Conjugated antibody (bs-2333R-Cy5.5)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul  
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-2333R-Cy5.5
    英文名稱 Rabbit Anti-NPRC/Cy5.5 Conjugated antibody
    中文名稱 Cy5.5標記的利鈉肽受體C抗體
    別    名 ANP C; ANPC; ANPRC; Atrial natriuretic peptide C type receptor; Atrionatriuretic peptide receptor C; Natriuretic peptide receptor C/guanylate cyclase C; NPR 3; NPR C; NPR3; NPRC; ANPRC_HUMAN.   
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul  
    研究領域 心血管  細胞生物  免疫學  細胞膜受體  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 Human, Mouse,  (predicted: Rat, Cow, Horse, )
    產品應用 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 57kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human NPR-C
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產品介紹 background:
    Natriuretic peptide receptor C does not exhibit guanylate cyclase activity. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction.

    Function:
    Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.

    Subunit:
    Homodimer; disulfide-linked. Dimers can also be formed through the C-terminal cysteine of isoform 2.

    Subcellular Location:
    Membrane; Single-pass type I membrane protein.

    Similarity:
    Belongs to the ANF receptor family.

    Database links:

    Entrez Gene: 281358 Cow

    Entrez Gene: 4883 Human

    Entrez Gene: 18162 Mouse

    Entrez Gene: 25339 Rat

    Omim: 108962 Human

    SwissProt: P10730 Cow

    SwissProt: P17342 Human

    SwissProt: P70180 Mouse

    SwissProt: P41740 Rat

    Unigene: 237028 Human

    Unigene: 619466 Human

    Unigene: 25259 Mouse

    Unigene: 11297 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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