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    產品中心-北京博奧森生物技術有限公司
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    Rabbit Anti-BCL2L10/Cy5 Conjugated antibody (bs-5796R-Cy5)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul  
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-5796R-Cy5
    英文名稱 Rabbit Anti-BCL2L10/Cy5 Conjugated antibody
    中文名稱 Cy5標記的BCL2樣10促凋亡蛋白抗體
    別    名 Anti apoptotic protein NrH; Anti-apoptotic protein NrH; Apoptosis regulator Bcl B; Apoptosis regulator Bcl-B; B2L10_HUMAN; BCL B; Bcl-2-like protein 10; Bcl2 L 10; BCL2 like 10 (apoptosis facilitator); BCL2 like 10 protein; Bcl2-L-10; Bcl2l10; BCLB; Boo; Diva; MGC129810; MGC129811; Nrh.   
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul  
    研究領域 腫瘤  細胞生物  免疫學  細胞凋亡  腫瘤細胞生物標志物  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit, )
    產品應用 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 22kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human BCL2L10
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產品介紹 background:
    Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. BCL2L10 is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human BCL2L10 protein is widely expressed. Also, the human BCL2L10 functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1.

    Function:
    Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK.

    Subunit:
    Binds to Bcl-2, Bcl-X and BAX. Interacts with APAF1.

    Subcellular Location:
    Mitochondrion. Nucleus membrane.

    Tissue Specificity:
    Widely expressed in adult tissues.

    Similarity:
    Belongs to the Bcl-2 family.

    Database links:

    Entrez Gene: 10017 Human

    Omim: 606910 Human

    SwissProt: Q9HD36 Human

    Unigene: 283672 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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