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    Rabbit Anti-NAV2/Gold Conjugated antibody (bs-11892R-Gold)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul(10nm  15nm  35nm
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-11892R-Gold
    英文名稱 Rabbit Anti-NAV2/Gold Conjugated antibody
    中文名稱 膠體金標記的維甲酸誘導神經母細胞瘤蛋白1抗體
    別    名 HELAD1; Helicase, APC down regulated 1; KIAA1419; mCG 145366; mKIAA3015; NAV 2; Neuron navigator 2; POMFIL2; Pore membrane and/or filament interacting like protein 2; RAINB1; RAINB2; Retinoic acid inducible in neuroblastoma 1; Steerin 2; STEERIN2; Unc 53 homolog 2; Unc53H2; NAV2_HUMAN.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul(10nm  15nm  35nm
    研究領域 腫瘤  細胞生物  神經生物學  腫瘤細胞生物標志物  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 Human,  (predicted: Mouse, Dog, Cow, Horse, Rabbit, )
    產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 268kDa
    性    狀 Lyophilized or Liquid
    濃    度 0.4mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human NAV2/RAINB1
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
    保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
    產品介紹 background:
    This gene encodes a member of the neuron navigator gene family, which may play a role in cellular growth and migration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

    Function:
    NAV2 protein shows high similarity to Caenorhabditis elegans, unc-53, that is required for axonal elongation of mechanosensory neurons, suggesting that these proteins are orthologs. Thus, NAV2 may be involved in the vitamin A metabolite, atRA (all-trans retinoic acid)-mediated neurite outgrowth. NAV2 possesses 3' to 5' helicase activity and exonuclease activity and is involved in the development of different sensory organs.

    Subcellular Location:
    Nuclear.

    Tissue Specificity:
    Highly expressed in the brain, kidney and liver. Also expressed in the thyroid, mammary gland, spinal cord, heart, placenta and lung. Abundantly expressed in colon cancers.

    Similarity:
    Belongs to the Nav/unc-53 family.
    Contains 1 CH (calponin-homology) domain.

    Database links:

    Entrez Gene: 89797 Human

    Omim: 607026 Human

    SwissProt: Q8IVL1 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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