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    Rabbit Anti-NPFF1 Receptor/Cy5 Conjugated antibody (bs-12018R-Cy5)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul  
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-12018R-Cy5
    英文名稱 Rabbit Anti-NPFF1 Receptor/Cy5 Conjugated antibody
    中文名稱 Cy5標記的G蛋白偶聯受體147抗體
    別    名 NPFF1 Receptor; G Protein Coupled Receptor 147; G-protein coupled receptor 147; GPR147; Neuropeptide FF receptor 1; NPFF1; NPFF1_HUMAN; NPFF1R1; NPFFR1; RFamide related peptide receptor OT7T022; RFamide-related peptide receptor OT7T022.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul  
    研究領域 細胞生物  神經生物學  信號轉導  細胞膜受體  G蛋白偶聯受體  G蛋白信號  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, Rabbit, Sheep, )
    產品應用 ICC=1:50-200 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 48kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human GPR147/NPFF1 Receptor (181-225aa)
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產品介紹 background:
    Neuropeptide FF 1 Receptor (NPFF1 or hFF1) and Neuropeptide FF 2 Receptor (NPFF2) belong to the G protein-coupled receptor 1 family. Both NPFF1 and NPFF2 are integral membrane proteins that act as receptors for NPAF (A-18- F-amide) and NPFF (F-8-F-amide) neuropeptides. Both NPFF proteins may be activated by synthetic or naturally occurring FMRF-amide-like ligands. The receptors are mediated by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. NPFF1 Receptors is highly expressed in the human hypothalamus and amygdala, indicating a possible role for NPFF1 in central autonomic and neuroendocrine control in the human brain. Based in part on NPFF2 Receptor expression in diencephalon and superficial layers of the spinal cord, NPFF2 Receptor is thought to be involved in the modulation of sensory input and opioid analgesia.

    Function:
    Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

    Subcellular Location:
    Cell membrane.

    Similarity:
    Belongs to the G-protein coupled receptor 1 family.

    Database links:

    Entrez Gene: 64106 Human

    Entrez Gene: 64107 Rat

    Omim: 607448 Human

    SwissProt: Q9GZQ6 Human

    SwissProt: Q9EP86 Rat

    Unigene: 302026 Human

    Unigene: 64483 Rat




    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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