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    Rabbit Anti-DEFB121/BF594 Conjugated antibody (bs-14251R-BF594)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul  
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-14251R-BF594
    英文名稱 Rabbit Anti-DEFB121/BF594 Conjugated antibody
    中文名稱 BF594標記的防御素β-121/β-defensin 121抗體
    別    名 beta 121; Beta-defensin 121; Beta-defensin 21; DB121_HUMAN; DEFB-21; DEFB121; Defensin; defensin, beta 121; defensin, beta 21; ESC42RELC.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul  
    研究領域 細胞生物  免疫學  發育生物學  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 Human, 
    產品應用 ICC=1:50-200 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 6.8kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human DEFB121
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產品介紹 background:
    Beta-defensins are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. The family of Beta-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many Beta-defensins also are involved in sperm maturation and capacitation. Beta-defensin 121 is a 76 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active. While expressed at low levels in testis, Beta-defensin 121 is abundantly expressed in epididymal caput and corpus and, unlike other Beta-defensins, it does not appear to be regulated by androgens.

    Function:
    Has antibacterial activity.

    Subcellular Location:
    Secreted.

    Similarity:
    Belongs to the beta-defensin family.

    Database links:

    Entrez Gene: 245934 Human

    SwissProt: Q5J5C9 Human

    Unigene: 272294 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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