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    Rabbit Anti-Lymphotoxin Beta/APC Conjugated antibody (bs-10063R-APC)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul  
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-10063R-APC
    英文名稱 Rabbit Anti-Lymphotoxin Beta/APC Conjugated antibody
    中文名稱 APC標記的腫瘤壞死因子C/淋巴毒素β抗體
    別    名 LT beta; LT-beta; LTB; lymphotoxin beta (TNF superfamily, member 3); lymphotoxin beta; lymphotoxin-beta; OTTHUMP00000038214; p33; TNF C; TNF-C; TNFC; TNFC_HUMAN; TNFSF3; tumor necrosis factor C (lymphotoxin beta); tumor necrosis factor C; tumor necrosis factor ligand superfamily member 3.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul  
    研究領域 腫瘤  免疫學  信號轉導  生長因子和激素  細胞因子  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, )
    產品應用
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 25kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Lymphotoxin Beta
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產品介紹 background:
    Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex and this complex is the primary ligand for the lymphotoxin-beta receptor. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is probably non-functional. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Function:
    Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional.

    Subunit:
    Heterotrimer of either two LTB and one LTA subunits or (less prevalent) one LTB and two LTA subunits.

    Subcellular Location:
    Membrane; Single-pass type II membrane protein (Potential).

    Tissue Specificity:
    Spleen and thymus.

    Similarity:
    Belongs to the tumor necrosis factor family.

    Database links:

    Entrez Gene: 4050 Human

    Entrez Gene: 16994 Mouse

    Omim: 600978 Human

    SwissProt: Q06643 Human

    SwissProt: P41155 Mouse

    Unigene: 376208 Human

    Unigene: 1715 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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