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    Rabbit Anti-EMR4/Gold Conjugated antibody (bs-14589R-Gold)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul(10nm  15nm  35nm
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-14589R-Gold
    英文名稱 Rabbit Anti-EMR4/Gold Conjugated antibody
    中文名稱 膠體金標記的EMR4蛋白抗體
    別    名 EGF like module containing mucin like hormone receptor like 4; EGF TM7 receptor EMR4; EMR4P; EMR4_HUMAN; FIRE; G protein coupled receptor 127; G protein coupled receptor PGR16; GPR127; PGR16; Putative EGF like module containing mucin like hormone receptor like 4.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul(10nm  15nm  35nm
    研究領域 信號轉導  細胞粘附分子  G蛋白偶聯受體  G蛋白信號  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 (predicted: Human, Mouse, Rat, Cow, Sheep, )
    產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 49kDa
    性    狀 Lyophilized or Liquid
    濃    度 0.4mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human EMR4
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
    保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
    產品介紹 background:
    This gene is a member of the EGF-TM7 receptor gene family which is thought to play a role in leukocyte adhesion and migration. In other vertebrates, including nonhuman primates, this gene encodes a protein containing N-terminal EGF domains and a C-terminal transmembrane domain. Sequence evidence for the human gene, however, indicates nucleotide deletion in the genomic sequence would result in frameshift and early termination of translation. A protein expressed by this gene would be soluble rather than expressed on the cell surface. As the encoded protein has not been detected, this gene may represent a transcribed pseudogene. [provided by RefSeq, Aug 2008]

    Function:
    EMR4 could mediate the cellular interaction between myeloid cells and B-cells.

    Subunit:
    Forms a heterodimer, consisting of a large extracellular region (alpha subunit) non-covalently linked to a seven-transmembrane moiety (beta subunit) (By similarity).

    Subcellular Location:
    Cell Membrane; multi pass membrane protein

    Post-translational modifications:
    Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit (By similarity).

    Similarity:
    Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    Contains 2 EGF-like domains.
    Contains 1 GPS domain.

    Database links:

    Entrez Gene: 326342 Human

    Omim: 612305 Human

    SwissProt: Q86SQ3 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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