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    Rabbit Anti-ZNF687/Gold Conjugated antibody (bs-16514R-Gold)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul(10nm  15nm  35nm
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-16514R-Gold
    英文名稱 Rabbit Anti-ZNF687/Gold Conjugated antibody
    中文名稱 膠體金標記的鋅指蛋白687抗體
    別    名 4931408L03Rik; DKFZp781I1719; KIAA1441; mKIAA1441; RP11-126K1.3; Zfp687; Zinc finger protein 687; ZN687_HUMAN; ZNF687.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul(10nm  15nm  35nm
    研究領域 轉錄調節因子  鋅指蛋白  表觀遺傳學  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 Human, 
    產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 129kDa
    性    狀 Lyophilized or Liquid
    濃    度 0.4mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human ZNF687
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
    保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
    產品介紹 background:
    Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF687 (zinc finger protein 687) is a 1,237 amino acid nuclear protein that is involved in transcriptional regulation. A member of the Krüppel C2H2-type zinc-finger protein family, ZNF687 contains ten C2H2-type zinc fingers and exists as two alternatively spliced isoforms. The gene encoding ZNF687 maps to human chromosome 1, which comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.

    Function:
    May be involved in transcriptional regulation.

    Subcellular Location:
    Nucleus.

    Similarity:
    Belongs to the krueppel C2H2-type zinc-finger protein family.
    Contains 10 C2H2-type zinc fingers.

    Database links:

    Entrez Gene: 57592 Human

    Entrez Gene: 78266 Mouse

    Omim: 610568 Human

    SwissProt: Q8N1G0 Human

    SwissProt: Q9D2D7 Mouse

    Unigene: 186756 Human

    Unigene: 389478 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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