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    Rabbit Anti-Kv1.2/Gold Conjugated antibody (bs-16865R-Gold)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul(10nm  15nm  35nm
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-16865R-Gold
    英文名稱 Rabbit Anti-Kv1.2/Gold Conjugated antibody
    中文名稱 膠體金標記的電壓門控鉀通道Kv1.2抗體
    別    名 Akr6a4; BK2; HBK5; HK4; HUKIV; Kca1 2; kcna2; KV1.2; MGC50217; Mk 2; MK2; NGK1; Potassium voltage gated channel shaker related subfamily member 2; Potassium voltage-gated channel subfamily A member 2; RBK2; Voltage gated potassium channel subunit Kv1.2. KCNA2_HUMAN   
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul(10nm  15nm  35nm
    研究領域 心血管  細胞生物  神經生物學  通道蛋白  細胞膜蛋白  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, )
    產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 57kDa
    性    狀 Lyophilized or Liquid
    濃    度 0.4mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Kv1.2
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
    保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
    產品介紹 background:
    Kv1.2 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which K(+) ions may pass in accordance with their electrochemical gradient. Kv1.2 binds PDZ domains of DLG1, DLG2 and DLG4. The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.

    Function:
    Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.

    Subunit:
    Heterotetramer of potassium channel proteins.

    Subcellular Location:
    Membrane; Multi-pass membrane protein

    Similarity:
    Belongs to the potassium channel family.

    Database links:

    Entrez Gene: 395117 Chicken

    Entrez Gene: 3737 Human

    Entrez Gene: 16490 Mouse

    Entrez Gene: 25468 Rat

    Omim: 176262 Human

    SwissProt: P16389 Human

    SwissProt: P63141 Mouse

    SwissProt: P63142 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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