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    Rabbit Anti-GRHL1/Gold Conjugated antibody (bs-16305R-Gold)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
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    說 明 書: 100ul(10nm  15nm  35nm
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-16305R-Gold
    英文名稱 Rabbit Anti-GRHL1/Gold Conjugated antibody
    中文名稱 膠體金標記的GRHL1蛋白抗體
    別    名 Grainyhead-like protein 1 homolog; grhl1; GRHL1_HUMAN; LBP32; Mammalian grainyhead; MGR; NH32; TFCP2L2; Transcription factor CP2-like 2; Transcription factor LBP-32.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul(10nm  15nm  35nm
    研究領域 細胞生物  發育生物學  轉錄調節因子  表觀遺傳學  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
    產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 70kDa
    性    狀 Lyophilized or Liquid
    濃    度 0.4mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human GRHL1
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
    保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
    產品介紹 background:
    This gene encodes a member of the grainyhead family of transcription factors. The encoded protein can exist as a homodimer or can form heterodimers with sister-of-mammalian grainyhead or brother-of-mammalian grainyhead. This protein functions as a transcription factor during development. [provided by RefSeq, Jun 2009]

    Function:
    Transcription factor. Isoform 1 may function as an activator and isoform 2 as a repressor in tissues where both forms are expressed. May play a role in development. May be involved in epidermal differentiation (By similarity). Binds and transactivates the EN1 promoter.

    Subcellular Location:
    Nucleus.

    Tissue Specificity:
    Isoform 1 is highly expressed in brain, pancreas, tonsil, placenta and kidney. Isoform 2 is highly expressed in brain and liver. Highly expressed in placental JEG-3 cells and at very low levels in non-steroidogenic cells. No expression detected in adrenal NCI-H295A cells.

    Similarity:
    Belongs to the grh/CP2 family. Grainyhead subfamily.

    Database links:

    Entrez Gene: 29841 Human

    Entrez Gene: 195733 Mouse

    Entrez Gene: 313993 Rat

    Omim: 609786 Human

    SwissProt: Q9NZI5 Human

    SwissProt: Q921D9 Mouse

    Unigene: 418493 Human

    Unigene: 263068 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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