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    Rabbit Anti-OSCAR/Gold Conjugated antibody (bs-17523R-Gold)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul(10nm  15nm  35nm
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-17523R-Gold
    英文名稱 Rabbit Anti-OSCAR/Gold Conjugated antibody
    中文名稱 膠體金標記的破骨細胞相關受體抗體
    別    名 hOSCAR; hOSCARM2; hOSCARM3; mOSCAR; Oscar; Oscar protein; OSCAR_HUMAN; OSCARS1; OSCARS2; Osteoclast associated immunoglobulin like receptor; Osteoclast associated receptor; Osteoclast-associated immunoglobulin-like receptor; Osteoclast-associated receptor; PIgR-3; PIGR3; Poly Ig receptor 3; Poly-Ig receptor 3; Polymeric immunoglobulin receptor 3.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul(10nm  15nm  35nm
    研究領域 細胞生物  免疫學  細胞類型標志物  t-淋巴細胞  b-淋巴細胞  細胞骨架  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 (predicted: Human, Mouse, Rat, )
    產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 28kDa
    性    狀 Lyophilized or Liquid
    濃    度 0.4mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human OSCAR
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
    保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
    產品介紹 background:
    Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]

    Function:
    Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation.

    Subcellular Location:
    Secreted and Cell membrane.

    Similarity:
    Belongs to the leukocyte receptor complex/polymeric immunogobulin receptor (PIR/LRC) family.
    Contains 2 Ig-like (immunoglobulin-like) domains.

    Database links:

    Entrez Gene: 126014 Human

    Omim: 606862 Human

    SwissProt: Q8IYS5 Human

    Unigene: 347655 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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