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    Rabbit Anti-SIDT1/Gold Conjugated antibody (bs-17484R-Gold)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul(10nm  15nm  35nm
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-17484R-Gold
    英文名稱 Rabbit Anti-SIDT1/Gold Conjugated antibody
    中文名稱 膠體金標記的SIDT1蛋白抗體
    別    名 AW045928; B830021E24Rik; FLJ20174; Msid2; OTTMUSP00000032144; SID 1; SID1; SID-1; SID1 transmembrane family member 1; SID1 transmembrane family, member 1; SIDT1; SIDT1_HUMAN.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul(10nm  15nm  35nm
    研究領域 腫瘤  細胞生物  跨膜蛋白  細胞膜蛋白  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Rabbit, )
    產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 92kDa
    性    狀 Lyophilized or Liquid
    濃    度 0.4mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human SIDT1
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
    保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
    產品介紹 background:
    SID-1 and SID-2 belong to the systemic RNA interference defective-1 (SID1) family of transmembrane proteins. SID-1, originally identified in C. elegans, is an 827 amino acid protein. It localizes to the cell membrane and contains eleven transmembrane domains. This suggests that SID-1 possibly functions as a channel protein. The overexpression of SID-1 enhances double stranded RNA (dsRNA) uptake in pancreatic ductal adenocarcinoma cells. SID-2, also first identified in C. elegans, is an 832 amino acid protein with multiple transmembrane domains. At least two isoforms exist for SID-2 due to alternative splicing. Isoform 2 contains an additional 21 amino acids after residue 387 and has an alternate sequence that is 8 amino acids shorter for residues 814 to 832 of isoform 1.

    Subcellular Location:
    Membrane.

    Similarity:
    Belongs to the SID1 family.

    Database links:

    Entrez Gene: 54847 Human

    Entrez Gene: 320007 Mouse

    Entrez Gene: 288109 Rat

    Omim: 606816 Human

    SwissProt: Q9NXL6 Human

    SwissProt: Q6AXF6 Mouse

    SwissProt: Q6Q3F5 Rat

    Unigene: 591291 Human

    Unigene: 242144 Mouse

    Unigene: 51246 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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