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    Rabbit Anti-NUP88/RBITC Conjugated antibody (bs-10782R-RBITC)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul  
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-10782R-RBITC
    英文名稱 Rabbit Anti-NUP88/RBITC Conjugated antibody
    中文名稱 羅丹明(RBITC)標記的核孔復合體蛋白88抗體
    別    名 karyoporin; Nuclear pore complex protein 88; Nuclear pore complex protein88; Nucleoporin 88; Nucleoporin 88 kDa; Nucleoporin 88kDa; Nucleoporin88; Nucleoporin88kDa; Nup 84; NUP 88; Nup84; Prei 2; Prei2; Preimplantation protein 2; Preimplantation protein2; NUP88_HUMAN.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul  
    研究領域 腫瘤  染色質和核信號  信號轉導  腫瘤細胞生物標志物  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, )
    產品應用 ICC=1:50-200 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 85kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human NUP88
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產品介紹 background:
    NUP88 is a nucleoporin that is an essential component of the nuclear pore complex. It interacts with NUP214/CAN, and is phosphorylated following DNA damage, possibly via the ATM/ATR pathway. NUP88 is also a tumour marker as it is overexpressed in a large number of malignant neoplasms and precancerous dysplasias.

    Function:
    Essential component of nuclear pore complex.

    Subunit:
    Interacts with NUP214/CAN.

    Subcellular Location:
    Nucleus, nuclear pore complex.

    Post-translational modifications:
    Phosphorylated upon DNA damage, probably by ATM or ATR.

    Database links:

    Entrez Gene: 4927 Human

    Entrez Gene: 19069 Mouse

    Entrez Gene: 113929 Rat

    Omim: 602552 Human

    SwissProt: Q99567 Human

    SwissProt: Q8CEC0 Mouse

    SwissProt: O08658 Rat

    Unigene: 584784 Human

    Unigene: 288962 Mouse

    Unigene: 11042 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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