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    Rabbit Anti-Glycine Receptor alpha 3/PE-Cy5 Conjugated antibody (bs-20548R-PE-Cy5)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul  
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-20548R-PE-Cy5
    英文名稱 Rabbit Anti-Glycine Receptor alpha 3/PE-Cy5 Conjugated antibody
    中文名稱 PE-Cy5標記的甘氨酸受體α3/GlyR α3抗體
    別    名 GLRA3; GLRA 3; Glra3; GLRA3_HUMAN; Glycine receptor alpha 3 polypeptide; Glycine receptor alpha 3 subunit; Glycine receptor subunit alpha 3; Glycine receptor subunit alpha-3; Ligand gated ion channel.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul  
    研究領域 神經生物學  通道蛋白  細胞膜受體  G蛋白偶聯受體  G蛋白信號  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 (predicted: Human, Mouse, Rat, )
    產品應用 ICC=1:50-200 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 50kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Glycine Receptor alpha 3
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產品介紹 background:
    The GLRA3 gene encodes the alpha-3 subunit of the neuronal glycine receptor, a ligand-gated chloride channel composed of ligand-binding alpha and structural beta polypeptides (Kingsmore et al., 1994 [PubMed 7894176]).[supplied by OMIM, Nov 2009]

    Function:
    The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).

    Subunit:
    Pentamer composed of alpha and beta subunits

    Subcellular Location:
    Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

    Tissue Specificity:
    Widely distributed throughout the central nervous system.

    Similarity:
    Belongs to the ligand-gated ion channel (TC 1.A.9) family.
    Glycine receptor (TC 1.A.9.3) subfamily. GLRA3 sub-subfamily.

    Database links:

    Entrez Gene: 8001 Human

    Entrez Gene: 110304 Mouse

    Omim: 600421 Human

    SwissProt: O75311 Human

    SwissProt: Q91XP5 Mouse

    Unigene: 413099 Human

    Unigene: 307061 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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