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    Rabbit Anti-SMCR7/HRP Conjugated antibody (bs-12633R-HRP)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul  
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-12633R-HRP
    英文名稱 Rabbit Anti-SMCR7/HRP Conjugated antibody
    中文名稱 辣根過氧化物酶標記的SMCR7蛋白抗體
    別    名 MGC23130; MID49; MIEF2; Mitochondrial dynamic protein MID49; Mitochondrial dynamic protein of 49 kDa; Mitochondrial elongation factor 2; Smith Magenis syndrome chromosome region candidate 7; Smith-Magenis syndrome chromosomal region candidate gene 7 protein.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul  
    研究領域 細胞生物  免疫學  發育生物學  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 Mouse,  (predicted: Human, Dog, Cow, Horse, Rabbit, Sheep, )
    產品應用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 49kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human SMCR7
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產品介紹 background:
    This gene encodes an outer mitochondrial membrane protein that functions in the regulation of mitochondrial morphology. It can directly recruit the fission mediator dynamin-related protein 1 (Drp1) to the mitochondrial surface. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]

    Function:
    Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity.

    Subcellular Location:
    Mitochondrion outer membrane; Single-pass membrane protein. Colocalizes with DNM1L at mitochondrial membrane. Forms foci and rings around mitochondria.

    Tissue Specificity:
    Expressed in all tissues tested with highest expression in heart and skeletal muscle.

    Similarity:
    Belongs to the MID49/MID51 family.

    Database links:

    Entrez Gene: 125170 Human

    Entrez Gene: 497916 Rat

    SwissProt: Q96C03 Human

    Unigene: 655555 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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