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    Rabbit Anti-TPSG1/APC Conjugated antibody (bs-12684R-APC)
    訂購熱線:400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術支持:techsupport@bioss.com.cn
    說 明 書: 100ul  
    100ul/2980.00元
    大包裝/詢價
    產品編號 bs-12684R-APC
    英文名稱 Rabbit Anti-TPSG1/APC Conjugated antibody
    中文名稱 APC標記的膜類胰蛋白酶1抗體
    別    名 gamma I; gamma II; lung tryptase; mast cell protease II; mast cell tryptase; pituitary tryptase; PRSS31; Serine protease 31; skin tryptase; TMT; Tpsg1; Transmembrane tryptase; trpA; TRYG1_HUMAN; Tryptase gamma (EC:3.4.21.-); tryptase gamma 1; tryptase gamma; Tryptase gamma heavy chain; tryptase gamma I; tryptase gamma II; Tryptase gamma light chain.  
    規格價格 100ul/2980元 購買        大包裝/詢價
    說 明 書 100ul  
    研究領域 細胞生物  泛素  細胞膜蛋白  
    抗體來源 Rabbit
    克隆類型 Polyclonal
    交叉反應 (predicted: Human, Mouse, )
    產品應用 ICC=1:50-200 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 32kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human TPSG1
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產品介紹 background:
    Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. There is uncertainty regarding the number of genes in this cluster. Currently four functional genes - alpha I, beta I, beta II and gamma I - have been identified. And beta I has an allelic variant named alpha II, beta II has an allelic variant beta III, also gamma I has an allelic variant gamma II. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha-tryptases predominant. This gene differs from other members of the tryptase gene family in that it has C-terminal hydrophobic domain, which may serve as a membrane anchor. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq, Jul 2008]

    Subcellular Location:
    Membrane.

    Tissue Specificity:
    Expressed in many tissues.

    Similarity:
    Belongs to the peptidase S1 family.
    Tryptase subfamily.
    Contains 1 peptidase S1 domain.

    Database links:

    Entrez Gene: 25823 Human

    Entrez Gene: 26945 Mouse

    Entrez Gene: 302990 Rat

    Omim: 609341 Human

    SwissProt: Q9NRR2 Human

    SwissProt: Q9QUL7 Mouse

    Unigene: 592076 Human

    Unigene: 180108 Mouse

    Unigene: 163109 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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